Friday, October 29, 2010

Difference between diclofenac sod. and potessium salt ......

Dilcofenic is a relatively potent NSAID. It is a phenylacetic or benzeneacetic acid derivative with the chemically designation 2-(2,6-dichlorophenyl)amino phenylacetic acid or benzeneacetic acid, monosodium or monopotassium salt. Diclofenac sodium was first synthesised by Ciba-Geigy of Switzerland in 1965 and was launched as Voltaren in 1988.

The sodium salt and potassium salt of diclofenac used are biologically equivalent, with both being protonated by the acid in the stomach. One difference is that diclofenac potassium is slightly more soluble in water than diclofenac sodium.


source-www.drugs.com, www.assistpainrelief.com

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